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Simultaneous Neutralization and Innate Immune Detection of a Replicating Virus by TRIM21
Tripartite motif-containing 21 (TRIM21) is a cytosolic immunoglobulin receptor that mediates antibody-dependent intracellular neutralization (ADIN). Here we show that TRIM21 potently inhibits the spreading infection of a replicating cytopathic virus and activates innate immunity. We used a quantitat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700317/ https://ncbi.nlm.nih.gov/pubmed/23596308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00647-13 |
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