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The Interaction of the Cellular Export Adaptor Protein Aly/REF with ICP27 Contributes to the Efficiency of Herpes Simplex Virus 1 mRNA Export

Herpes simplex virus 1 (HSV-1) protein ICP27 enables viral mRNA export by accessing the cellular mRNA export receptor TAP/NXF, which guides mRNA through the nuclear pore complex. ICP27 binds viral mRNAs and interacts with TAP/NXF, providing a link to the cellular mRNA export pathway. ICP27 also inte...

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Bibliographische Detailangaben
Hauptverfasser: Tian, Xiaochen, Devi-Rao, Gayathri, Golovanov, Alexander P., Sandri-Goldin, Rozanne M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700301/
https://ncbi.nlm.nih.gov/pubmed/23637401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00738-13
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