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Overlapping motifs on the herpes viral proteins ICP27 and ORF57 mediate interactions with the mRNA export adaptors ALYREF and UIF

The TREX complex mediates the passage of bulk cellular mRNA export to the nuclear export factor TAP/NXF1 via the export adaptors ALYREF or UIF, which appear to act in a redundant manner. TREX complex recruitment to nascent RNA is coupled with 5′ capping, splicing and polyadenylation. Therefore to fa...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Tunnicliffe, Richard B., Tian, Xiaochen, Storer, Joanna, Sandri-Goldin, Rozanne M., Golovanov, Alexander P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177440/
https://ncbi.nlm.nih.gov/pubmed/30301920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33379-x
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