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The Cellular RNA Export Receptor TAP/NXF1 Is Required for ICP27-Mediated Export of Herpes Simplex Virus 1 RNA, but the TREX Complex Adaptor Protein Aly/REF Appears To Be Dispensable

Herpes simplex virus 1 (HSV-1) protein ICP27 has been shown to shuttle between the nucleus and cytoplasm and to bind viral RNA during infection. ICP27 was found to interact with the cellular RNA export adaptor protein Aly/REF, which is part of the TREX complex, and to relocalize Aly/REF to viral rep...

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Detalhes bibliográficos
Main Authors: Johnson, Lisa A., Li, Ling, Sandri-Goldin, Rozanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698537/
https://ncbi.nlm.nih.gov/pubmed/19369354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00375-09
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