Monoclonal Antibodies Combined with Adenovirus-Vectored Interferon Significantly Extend the Treatment Window in Ebola Virus-Infected Guinea Pigs

Monoclonal antibodies (MAbs) are currently a promising treatment strategy against Ebola virus infection. This study combined MAbs with an adenovirus-vectored interferon (DEF201) to evaluate the efficacy in guinea pigs and extend the treatment window obtained with MAbs alone. Initiating the combinati...

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Autors principals: Qiu, Xiangguo, Wong, Gary, Fernando, Lisa, Ennis, Jane, Turner, Jeffrey D., Alimonti, Judie B., Yao, Xiaojian, Kobinger, Gary P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700280/
https://ncbi.nlm.nih.gov/pubmed/23616649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00173-13
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