Recombinant IgA Is Sufficient To Prevent Influenza Virus Transmission in Guinea Pigs

A serum hemagglutination inhibition (HAI) titer of 40 or greater is thought to be associated with reduced influenza virus pathogenesis in humans and is often used as a correlate of protection in influenza vaccine studies. We have previously demonstrated that intramuscular vaccination of guinea pigs...

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Hauptverfasser: Seibert, Christopher W., Rahmat, Saad, Krause, Jens C., Eggink, Dirk, Albrecht, Randy A., Goff, Peter H., Krammer, Florian, Duty, J. Andrew, Bouvier, Nicole M., García-Sastre, Adolfo, Palese, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700183/
https://ncbi.nlm.nih.gov/pubmed/23698296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00979-13
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