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Efficient Transmission of Pandemic H1N1 Influenza Viruses with High-Level Oseltamivir Resistance
The limited availability of approved influenza virus antivirals highlights the importance of studying the fitness and transmissibility of drug-resistant viruses. S247N is a novel, naturally occurring N1 neuraminidase mutation that reduces oseltamivir sensitivity and greatly potentiates oseltamivir r...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347392/ https://ncbi.nlm.nih.gov/pubmed/22345446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00151-12 |
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