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Efficient Transmission of Pandemic H1N1 Influenza Viruses with High-Level Oseltamivir Resistance

The limited availability of approved influenza virus antivirals highlights the importance of studying the fitness and transmissibility of drug-resistant viruses. S247N is a novel, naturally occurring N1 neuraminidase mutation that reduces oseltamivir sensitivity and greatly potentiates oseltamivir r...

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Detalhes bibliográficos
Main Authors: Seibert, Christopher W., Rahmat, Saad, Krammer, Florian, Palese, Peter, Bouvier, Nicole M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347392/
https://ncbi.nlm.nih.gov/pubmed/22345446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00151-12
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