Growth-dependent expression of dihydrofolate reductase mRNA from modular cDNA genes.

Dihydrofolate reductase (DHFR) synthesis is regulated in a growth-dependent fashion. Dividing cells synthesize DHFR at a 10-fold-higher rate than do stationary cells. To study this growth-dependent synthesis. DHFR genes have been constructed from a DHFR cDNA segment, the adenovirus major late promot...

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Bibliographic Details
Main Authors: Kaufman, R J, Sharp, P A
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC370013/
https://ncbi.nlm.nih.gov/pubmed/6138708
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