Activation of Extracellular Signal-Regulated Kinase but Not of p38 Mitogen-Activated Protein Kinase Pathways in Lymphocytes Requires Allosteric Activation of SOS

Thymocytes convert graded T cell receptor (TCR) signals into positive selection or deletion, and activation of extracellular signal-related kinase (ERK), p38, and Jun N-terminal protein kinase (JNK) mitogen-activated protein kinases (MAPKs) has been postulated to play a discriminatory role. Two fami...

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Detalhes bibliográficos
Main Authors: Jun, Jesse E., Yang, Ming, Chen, Hang, Chakraborty, Arup K., Roose, Jeroen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700092/
https://ncbi.nlm.nih.gov/pubmed/23589333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01593-12
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