Fluorescent sensors reporting the activity of ammonium transceptors in live cells

Ammonium serves as key nitrogen source and metabolic intermediate, yet excess causes toxicity. Ammonium uptake is mediated by ammonium transporters, whose regulation is poorly understood. While transport can easily be characterized in heterologous systems, measuring transporter activity in vivo rema...

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Bibliographic Details
Main Authors: De Michele, Roberto, Ast, Cindy, Loqué, Dominique, Ho, Cheng-Hsun, Andrade, Susana LA, Lanquar, Viviane, Grossmann, Guido, Gehne, Sören, Kumke, Michael U, Frommer, Wolf B
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2013
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699834/
https://ncbi.nlm.nih.gov/pubmed/23840931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00800
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