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Single-fluorophore membrane transport activity sensors with dual-emission read-out

We recently described a series of genetically encoded, single-fluorophore-based sensors, termed AmTrac and MepTrac, which monitor membrane transporter activity in vivo (De Michele et al., 2013). However, being intensiometric, AmTrac and Meptrac are limited in their use for quantitative studies. Here...

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Publicat a:eLife
Autors principals: Ast, Cindy, De Michele, Roberto, Kumke, Michael U, Frommer, Wolf B
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491562/
https://ncbi.nlm.nih.gov/pubmed/26090909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07113
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