A Ribokinase Family Conserved Monovalent Cation Binding Site Enhances the MgATP-induced Inhibition in E. coli Phosphofructokinase-2

The presence of a regulatory site for monovalent cations that affects the conformation of the MgATP-binding pocket leading to enzyme activation has been demonstrated for ribokinases. This site is selective toward the ionic radius of the monovalent cation, accepting those larger than Na(+). Phosphofr...

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Detalles Bibliográficos
Main Authors: Baez, Mauricio, Cabrera, Ricardo, Pereira, Humberto M., Blanco, Alejandro, Villalobos, Pablo, Ramírez-Sarmiento, César A., Caniuguir, Andrés, Guixé, Victoria, Garratt, Richard C., Babul, Jorge
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699746/
https://ncbi.nlm.nih.gov/pubmed/23823238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.028
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