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Interactions of the Auxilin-1 PTEN-like Domain with Model Membranes Result in Nanoclustering of Phosphatidyl Inositol Phosphates

Auxilin-1 is a neuron-specific membrane-binding protein involved in a late stage of clathrin-mediated endocytosis. It recruits Hsc70, thus initiating uncoating of the clathrin-coated vesicles. Interactions of auxilin-1 with the vesicle membrane are crucial for this function and are mediated via an N...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kalli, Antreas C., Morgan, Gareth, Sansom, Mark S.P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699743/
https://ncbi.nlm.nih.gov/pubmed/23823232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.012
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