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Defining the Membrane-Associated State of the PTEN Tumor Suppressor Protein
Phosphatase and tensin-homolog deleted on chromosome 10 (PTEN) is a tumor-suppressor protein that regulates phosphatidylinositol 3-kinase (PI3-K) signaling by binding to the plasma membrane and hydrolyzing the 3′ phosphate from phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P(3)) to form phosp...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566463/ https://ncbi.nlm.nih.gov/pubmed/23442912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.002 |
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