Measurement of Cationic and Intracellular Modulation of Integrin Binding Affinity by AFM-Based Nanorobot

Integrins are dynamic transmembrane cation-dependent heterodimers that both anchor cells in position and transduce signals into and out of cells. We used an atomic force microscope (AFM)-based nanorobotic system to measure integrin-binding forces in intact human intestinal epithelial Caco-2 cells. T...

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Bibliographische Detailangaben
Hauptverfasser: Patterson, Kevin C., Yang, Ruiguo, Zeng, Bixi, Song, Bo, Wang, Shouye, Xi, Ning, Basson, Marc D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Cell Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699737/
https://ncbi.nlm.nih.gov/pubmed/23823222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.052
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