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Anti-IL-5 Therapy Reduces Mast Cells and IL-9 Cells in Pediatric Eosinophilic Esophagitis
BACKGROUND: Eosinophilic esophagitis (EoE) is a clinicopathologic entity of increasing worldwide prevalence. IL-5 is essential for eosinophil trafficking and anti-IL-5 therapy decreases esophageal eosinophilia. EoE is associated with a prominent mast cell infiltration. OBJECTIVE: We investigated whe...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699422/ https://ncbi.nlm.nih.gov/pubmed/23623266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.02.042 |
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