Effects of Modulating M3 Muscarinic Receptor Activity on Azoxymethane-Induced Liver Injury in Mice

Previously, we reported that azoxymethane (AOM)-induced liver injury is robustly exacerbated in M3 muscarinic receptor (M3R)-deficient mice. We used the same mouse model to test the hypothesis that selective pharmacological modulation of M3R activity regulates the liver injury response. Initial expe...

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Hauptverfasser: Khurana, Sandeep, Jadeja, Ravirajsinh, Twadell, William, Cheng, Kunrong, Rachakonda, Vikrant, Saxena, Neeraj, Raufman, Jean-Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699334/
https://ncbi.nlm.nih.gov/pubmed/23707755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.05.010
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