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Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts

Hox genes are key regulators of development. In mammals, the study of these genes is greatly confounded by their large number, overlapping functions and interspersed shared enhancers. Here, we describe the use of a novel recombineering strategy to introduce simultaneous frameshift mutations into the...

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Bibliografiske detaljer
Main Authors: Raines, Anna M., Adam, Mike, Magella, Bliss, Meyer, Sara E., Grimes, H. Leighton, Dey, Sudhansu K., Potter, S. Steven
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699281/
https://ncbi.nlm.nih.gov/pubmed/23760953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.092569
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