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Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts

Hox genes are key regulators of development. In mammals, the study of these genes is greatly confounded by their large number, overlapping functions and interspersed shared enhancers. Here, we describe the use of a novel recombineering strategy to introduce simultaneous frameshift mutations into the...

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Main Authors: Raines, Anna M., Adam, Mike, Magella, Bliss, Meyer, Sara E., Grimes, H. Leighton, Dey, Sudhansu K., Potter, S. Steven
格式: Artigo
語言:Inglês
出版: Company of Biologists 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699281/
https://ncbi.nlm.nih.gov/pubmed/23760953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.092569
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