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Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts

Hox genes are key regulators of development. In mammals, the study of these genes is greatly confounded by their large number, overlapping functions and interspersed shared enhancers. Here, we describe the use of a novel recombineering strategy to introduce simultaneous frameshift mutations into the...

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書誌詳細
主要な著者: Raines, Anna M., Adam, Mike, Magella, Bliss, Meyer, Sara E., Grimes, H. Leighton, Dey, Sudhansu K., Potter, S. Steven
フォーマット: Artigo
言語:Inglês
出版事項: Company of Biologists 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699281/
https://ncbi.nlm.nih.gov/pubmed/23760953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.092569
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