Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K(+) channel

Ovarian cancer remains the leading cause of death in women with gynecologic malignancies, despite surgical advances and the development of more effective chemotherapeutics. As increasing evidence indicates that clear-cell ovarian cancer may have unique pathogenesis, further understanding of molecula...

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Main Authors: Cicek, Mine S., Koestler, Devin C., Fridley, Brooke L., Kalli, Kimberly R., Armasu, Sebastian M., Larson, Melissa C., Wang, Chen, Winham, Stacey J., Vierkant, Robert A., Rider, David N., Block, Matthew S., Klotzle, Brandy, Konecny, Gottfried, Winterhoff, Boris J., Hamidi, Habib, Shridhar, Viji, Fan, Jian-Bing, Visscher, Daniel W., Olson, Janet E., Hartmann, Lynn C., Bibikova, Marina, Chien, Jeremy, Cunningham, Julie M., Goode, Ellen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699065/
https://ncbi.nlm.nih.gov/pubmed/23571109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt160
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