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Environmental Confounding in Gene-Environment Interaction Studies

We show that, in the presence of uncontrolled environmental confounding, joint tests for the presence of a main genetic effect and gene-environment interaction will be biased if the genetic and environmental factors are correlated, even if there is no effect of either the genetic factor or the envir...

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Detalles Bibliográficos
Main Authors: VanderWeele, Tyler J., Ko, Yi-An, Mukherjee, Bhramar
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698991/
https://ncbi.nlm.nih.gov/pubmed/23821317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kws439
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