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Case-only gene-environment interaction studies: when does association imply mechanistic interaction?

Case-only studies are often used to identify interactions between a genetic factor and an environmental factor under the assumption both factors are independent in the population. However, interpreting a statistical association between the genetic and the environmental factors among the cases as evi...

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Detalhes bibliográficos
Main Authors: VanderWeele, Tyler J., Hernández-Díaz, Sonia, Hernán, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112477/
https://ncbi.nlm.nih.gov/pubmed/20039380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20484
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