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Efficient Designs of Gene-Environment Interaction Studies: Implications of Hardy-Weinberg Equilibrium and Gene-Environment Independence
It is important to investigate whether genetic susceptible variants exercise the same effects in populations that are differentially exposed to environmental risk factors. Here, we assess the power of four two-phase case-control design strategies for assessing multiplicative gene-environment (G-E) i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448495/ https://ncbi.nlm.nih.gov/pubmed/22362617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4460 |
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