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Efficient Designs of Gene-Environment Interaction Studies: Implications of Hardy-Weinberg Equilibrium and Gene-Environment Independence

It is important to investigate whether genetic susceptible variants exercise the same effects in populations that are differentially exposed to environmental risk factors. Here, we assess the power of four two-phase case-control design strategies for assessing multiplicative gene-environment (G-E) i...

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書誌詳細
主要な著者: Chen, Jinbo, Kang, Guolian, VanderWeele, Tyler, Zhang, Cuilin, Mukherjee, Bhramar
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448495/
https://ncbi.nlm.nih.gov/pubmed/22362617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4460
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