Pervasive and Cooperative Deadenylation of 3’UTRs by Embryonic MicroRNA Families

To understand how miRNA-mediated silencing impacts on embryonic mRNAs, we conducted a functional survey of abundant maternal and zygotic miRNA families in the C. elegans embryo. We show that the miR-35-42, and the miR-51-56 miRNA families define maternal and zygotic miRNA-induced silencing complexes...

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Autors principals: Wu, Edlyn, Thivierge, Caroline, Flamand, Mathieu, Mathonnet, Geraldine, Vashisht, Ajay A., Wohlschlegel, James, Fabian, Marc R., Sonenberg, Nahum, Duchaine, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698950/
https://ncbi.nlm.nih.gov/pubmed/21095586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.003
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