Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers

CYP2A6 is the main nicotine metabolizing enzyme in humans. We investigated the relationships between CYP2A6 genotype, baseline plasma 3HC/COT (a phenotypic marker of CYP2A6 activity), and smoking behaviors in African-American light smokers. Cigarette consumption, age of initiation, and dependence sc...

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Detalhes bibliográficos
Main Authors: Ho, Man Ki, Mwenifumbo, Jill C., Koudsi, Nael Al, Okuyemi, Kolawole S., Ahluwalia, Jasjit S., Benowitz, Neal L., Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698861/
https://ncbi.nlm.nih.gov/pubmed/19279561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2009.19
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