Glucose Regulation of Load‐Induced mTOR Signaling and ER Stress in Mammalian Heart

BACKGROUND: Changes in energy substrate metabolism are first responders to hemodynamic stress in the heart. We have previously shown that hexose‐6‐phosphate levels regulate mammalian target of rapamycin (mTOR) activation in response to insulin. We now tested the hypothesis that inotropic stimulation...

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Bibliografiska uppgifter
Huvudupphovsmän: Sen, Shiraj, Kundu, Bijoy K., Wu, Henry Cheng‐Ju, Hashmi, S. Shahrukh, Guthrie, Patrick, Locke, Landon W., Roy, R. Jack, Matherne, G. Paul, Berr, Stuart S., Terwelp, Matthew, Scott, Brian, Carranza, Sylvia, Frazier, O. Howard, Glover, David K., Dillmann, Wolfgang H., Gambello, Michael J., Entman, Mark L., Taegtmeyer, Heinrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2013
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698799/
https://ncbi.nlm.nih.gov/pubmed/23686371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.004796
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