Glucose Regulation of Load‐Induced mTOR Signaling and ER Stress in Mammalian Heart

BACKGROUND: Changes in energy substrate metabolism are first responders to hemodynamic stress in the heart. We have previously shown that hexose‐6‐phosphate levels regulate mammalian target of rapamycin (mTOR) activation in response to insulin. We now tested the hypothesis that inotropic stimulation...

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Detaylı Bibliyografya
Asıl Yazarlar: Sen, Shiraj, Kundu, Bijoy K., Wu, Henry Cheng‐Ju, Hashmi, S. Shahrukh, Guthrie, Patrick, Locke, Landon W., Roy, R. Jack, Matherne, G. Paul, Berr, Stuart S., Terwelp, Matthew, Scott, Brian, Carranza, Sylvia, Frazier, O. Howard, Glover, David K., Dillmann, Wolfgang H., Gambello, Michael J., Entman, Mark L., Taegtmeyer, Heinrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2013
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698799/
https://ncbi.nlm.nih.gov/pubmed/23686371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.004796
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