Rifampicin Reduces Susceptibility to Ofloxacin in Rifampicin-resistant Mycobacterium tuberculosis through Efflux

RATIONALE: Central dogma suggests that rifampicin resistance in Mycobacterium tuberculosis develops solely through rpoB gene mutations. OBJECTIVE: To determine whether rifampicin induces efflux pumps activation in rifampicin resistant M. tuberculosis strains thereby defining rifampicin resistance le...

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Main Authors: Louw, Gail E., Warren, Robin M., van Pittius, Nicolaas C. Gey, Leon, Rosalba, Jimenez, Adelina, Hernandez-Pando, Rogelio, McEvoy, Christopher R. E., Grobbelaar, Melanie, Murray, Megan, van Helden, Paul D., Victor, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698754/
https://ncbi.nlm.nih.gov/pubmed/21512166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201011-1924OC
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