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Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation

The B″/PR72 family of protein phosphatase 2A (PP2A) is an important PP2A family involved in diverse cellular processes, and uniquely regulated by calcium binding to the regulatory subunit. The PR70 subunit in this family interacts with cell division control 6 (Cdc6), a cell cycle regulator important...

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Detalhes bibliográficos
Main Authors: Wlodarchak, Nathan, Guo, Feng, Satyshur, Kenneth A, Jiang, Li, Jeffrey, Philip D, Sun, Tingwan, Stanevich, Vitali, Mumby, Marc C, Xing, Yongna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698643/
https://ncbi.nlm.nih.gov/pubmed/23752926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.77
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