Restrictions to HIV-1 replication in resting CD4(+) T lymphocytes

CD4(+) T lymphocytes represent the main target cell population of human immunodeficiency virus (HIV). In an activated state, CD4(+) T cells residing in lymphoid organs are a major reservoir of ongoing HIV-1 replication in infected individuals. In contrast, resting CD4(+) T cells are highly resistant...

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Autori principali: Pan, Xiaoyu, Baldauf, Hanna-Mari, Keppler, Oliver T, Fackler, Oliver T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698640/
https://ncbi.nlm.nih.gov/pubmed/23732522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.74
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