Phenotypic Switching in Cells Transformed with the Herpes Simplex Virus Thymidine Kinase Gene

Biochemical transformation of Ltk(−) cells with the herpes simplex virus thymidine kinase (tk) gene resulted in numerous TK(+) colonies that survived selection in hypoxanthine-aminopterin-thymidine medium. Many of these TK(+) cells lines switched phenotypes and reverted to the TK(−) state. In this r...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Ostrander, Michael, Vogel, Steven, Silverstein, Saul
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1982
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369847/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14582166/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.6.708-714.1982
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