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Phenotypic Switching in Cells Transformed with the Herpes Simplex Virus Thymidine Kinase Gene
Biochemical transformation of Ltk(−) cells with the herpes simplex virus thymidine kinase (tk) gene resulted in numerous TK(+) colonies that survived selection in hypoxanthine-aminopterin-thymidine medium. Many of these TK(+) cells lines switched phenotypes and reverted to the TK(−) state. In this r...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1982
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC369847/ https://ncbi.nlm.nih.gov/pubmed/14582166 |
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