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Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.

Inhibition of herpes simplex virus (HSV) thymidine kinase (TK) gene transcription (pHSV-106, pML-BPV-TK4) by DNA methylation is an indirect effect, which occurs with a latency period of approximately equal to 8 hr after microinjection of the DNA into TK- rat 2 and mouse LTK- cells. We have strong ev...

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Detalhes bibliográficos
Main Authors: Buschhausen, G, Wittig, B, Graessmann, M, Graessmann, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC304389/
https://ncbi.nlm.nih.gov/pubmed/3029768
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