Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.
Inhibition of herpes simplex virus (HSV) thymidine kinase (TK) gene transcription (pHSV-106, pML-BPV-TK4) by DNA methylation is an indirect effect, which occurs with a latency period of approximately equal to 8 hr after microinjection of the DNA into TK- rat 2 and mouse LTK- cells. We have strong ev...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1987
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1177 |
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