Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.

Inhibition of herpes simplex virus (HSV) thymidine kinase (TK) gene transcription (pHSV-106, pML-BPV-TK4) by DNA methylation is an indirect effect, which occurs with a latency period of approximately equal to 8 hr after microinjection of the DNA into TK- rat 2 and mouse LTK- cells. We have strong ev...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Buschhausen, G, Wittig, B, Graessmann, M, Graessmann, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1177
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