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General method for cloning amplified DNA by differential screening with genomic probes.

Mutant Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate, a potent and specific inhibitor of aspartate transcarbamylase, have amplified the gene coding for the multifunctional protein (CAD) that includes this activity. The average amount of DNA amplified is approximately 500 kilo...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Brison, O, Ardeshir, F, Stark, G R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 1982
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369828/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6896736/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.5.578
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