General method for cloning amplified DNA by differential screening with genomic probes.

Mutant Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate, a potent and specific inhibitor of aspartate transcarbamylase, have amplified the gene coding for the multifunctional protein (CAD) that includes this activity. The average amount of DNA amplified is approximately 500 kilo...

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Hlavní autoři: Brison, O, Ardeshir, F, Stark, G R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1982
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC369828/
https://ncbi.nlm.nih.gov/pubmed/6896736
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