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Structure of amplified DNA in different Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate.

Syrian hamster cell lines selected in multiple steps for resistance to high levels of N-(phosphonacetyl)-L-aspartate (PALA) contain many copies of the gene coding for the pyrimidine pathway enzyme CAD. Approximately 500 kilobases of additional DNA was coamplified with each copy of the CAD gene in se...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ardeshir, F, Giulotto, E, Zieg, J, Brison, O, Liao, W S, Stark, G R
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6656763/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.11.2076
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