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Assessing Genome-Wide Statistical Significance for Large p Small n Problems

Assessing genome-wide statistical significance is an important issue in genetic studies. We describe a new resampling approach for determining the appropriate thresholds for statistical significance. Our simulation results demonstrate that the proposed approach accurately controls the genome-wide ty...

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Detalhes bibliográficos
Main Authors: Diao, Guoqing, Vidyashankar, Anand N.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697980/
https://ncbi.nlm.nih.gov/pubmed/23666935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.150896
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