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Assessing statistical significance in multivariable genome wide association analysis
Motivation: Although Genome Wide Association Studies (GWAS) genotype a very large number of single nucleotide polymorphisms (SNPs), the data are often analyzed one SNP at a time. The low predictive power of single SNPs, coupled with the high significance threshold needed to correct for multiple test...
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Publicado no: | Bioinformatics |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4920127/ https://ncbi.nlm.nih.gov/pubmed/27153677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw128 |
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