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Assessing Genome-Wide Statistical Significance for Large p Small n Problems
Assessing genome-wide statistical significance is an important issue in genetic studies. We describe a new resampling approach for determining the appropriate thresholds for statistical significance. Our simulation results demonstrate that the proposed approach accurately controls the genome-wide ty...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697980/ https://ncbi.nlm.nih.gov/pubmed/23666935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.150896 |
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