Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor

We evaluated the expression of tissue factor (TF) in ovarian cancer (EOC) and the potential of hI-con1, an antibody-like molecule targeting TF, as a novel form of therapy against chemotherapy-resistant ovarian disease. We studied the expression of TF in 88 EOC by immunohistochemistry (IHC) and real-...

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Hauptverfasser: Cocco, Emiliano, Varughese, Joyce, Buza, Natalia, Bellone, Stefania, Lin, Ken-Yu, Bellone, Marta, Todeschini, Paola, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Carrara, Luisa, Tassi, Renata, Pecorelli, Sergio, Lockwood, Charles J., Santin, Alessandro D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697933/
https://ncbi.nlm.nih.gov/pubmed/21725665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-011-9401-0
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