Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth

PURPOSE: Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immunosuppressive cells that are upregulated in cancer. Little is known about the prevalence and importance of MDSC in pancreas adenocarcinoma (PA). EXPERIMENTAL DESIGN: Peripheral blood, bone marrow, and tumor sample...

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Bibliografiske detaljer
Main Authors: Porembka, Matthew R., Mitchem, Jonathan B., Belt, Brian A., Hsieh, Chyi-Song, Lee, Hyang-Mi, Herndon, John, Gillanders, William E., Linehan, David C., Goedegebuure, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697836/
https://ncbi.nlm.nih.gov/pubmed/22215137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1178-0
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