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Carbamylation of Serum Albumin as a Risk Factor for Mortality in Patients with Kidney Failure
Urea, the toxic end-product of protein catabolism, is elevated in end-stage renal disease (ESRD), although it is unclear whether or how it contributes to disease. Urea can promote the carbamylation of proteins on multiple lysine side chains, including human albumin, which has a predominant carbamyla...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697767/ https://ncbi.nlm.nih.gov/pubmed/23467560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005218 |
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