Carbamylation of Serum Albumin as a Risk Factor for Mortality in Patients with Kidney Failure

Urea, the toxic end-product of protein catabolism, is elevated in end-stage renal disease (ESRD), although it is unclear whether or how it contributes to disease. Urea can promote the carbamylation of proteins on multiple lysine side chains, including human albumin, which has a predominant carbamyla...

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Detalhes bibliográficos
Main Authors: Berg, Anders H., Drechsler, Christiane, Wenger, Julia, Buccafusca, Roberto, Hod, Tammy, Kalim, Sahir, Ramma, Wenda, Parikh, Samir M., Steen, Hanno, Friedman, David J., Danziger, John, Wanner, Christoph, Thadhani, Ravi, Karumanchi, S. Ananth
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697767/
https://ncbi.nlm.nih.gov/pubmed/23467560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005218
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