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Protein Carbamylation in Kidney Disease: Pathogenesis and Clinical Implications
Carbamylation describes a non-enzymatic, posttranslational protein modification mediated by cyanate, a dissociation product of urea. When kidney function declines and urea accumulates, the burden of carbamylation naturally rises. Free amino acids may protect proteins from carbamylation, and protein...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209336/ https://ncbi.nlm.nih.gov/pubmed/25037561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.ajkd.2014.04.034 |
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