HipA-Triggered Growth Arrest and β-Lactam Tolerance in Escherichia coli Are Mediated by RelA-Dependent ppGpp Synthesis

Persistence is a phenomenon whereby a subpopulation of bacterial cells enters a transient growth-arrested state that confers antibiotic tolerance. While entrance into persistence has been linked to the activities of toxin proteins, the molecular mechanisms by which toxins induce growth arrest and th...

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Bibliografiska uppgifter
Huvudupphovsmän: Bokinsky, Gregory, Baidoo, Edward E. K., Akella, Swetha, Burd, Helcio, Weaver, Daniel, Alonso-Gutierrez, Jorge, García-Martín, Héctor, Lee, Taek Soon, Keasling, Jay D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697643/
https://ncbi.nlm.nih.gov/pubmed/23667235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02210-12
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