Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity

Obesity is associated with resistance to the actions of both leptin and insulin via mechanisms that remain incompletely understood. To investigate whether leptin resistance per se contributes to insulin resistance and impaired glucose homeostasis, we investigated the effect of acute leptin administr...

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Main Authors: Koch, Christiane, Augustine, Rachael A., Steger, Juliane, Ganjam, Goutham K., Benzler, Jonas, Pracht, Corinna, Lowe, Chrishanthi, Schwartz, Michael W., Shepherd, Peter R., Anderson, Greg M., Grattan, David R., Tups, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697436/
https://ncbi.nlm.nih.gov/pubmed/21123564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3202-10.2010
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