SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice

BACKGROUND: Energy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. To elucidate the possible mechanisms underlying these effects, a microarray-based transcriptomics approach was used to identify novel g...

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Vydáno v:Genes Nutr
Hlavní autoři: Sergi, Domenico, Campbell, Fiona M., Grant, Christine, Morris, Amanda C., Bachmair, Eva-Maria, Koch, Christiane, McLean, Fiona H., Muller, Aifric, Hoggard, Nigel, de Roos, Baukje, Porteiro, Begona, Boekschoten, Mark V., McGillicuddy, Fiona C., Kahn, Darcy, Nicol, Phyllis, Benzler, Jonas, Mayer, Claus-Dieter, Drew, Janice E., Roche, Helen M., Muller, Michael, Nogueiras, Ruben, Dieguez, Carlos, Tups, Alexander, Williams, Lynda M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263559/
https://ncbi.nlm.nih.gov/pubmed/30519364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12263-018-0619-1
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